3le2: Difference between revisions

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[[Image:3le2.png|left|200px]]


{{STRUCTURE_3le2|  PDB=3le2  |  SCENE=  }}
==Structure of Arabidopsis AtSerpin1. Native Stressed Conformation==
 
<StructureSection load='3le2' size='340' side='right'caption='[[3le2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===Structure of Arabidopsis AtSerpin1. Native Stressed Conformation===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3le2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LE2 FirstGlance]. <br>
{{ABSTRACT_PUBMED_20181955}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3le2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3le2 OCA], [https://pdbe.org/3le2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3le2 RCSB], [https://www.ebi.ac.uk/pdbsum/3le2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3le2 ProSAT]</span></td></tr>
[[3le2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LE2 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SPZX_ARATH SPZX_ARATH] Inhibits metacaspase-9 cysteine protease.<ref>PMID:17028019</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/le/3le2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3le2 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Serpin|Serpin]]
*[[Serpin 3D structures|Serpin 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:020181955</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Cumi, P M.G.]]
[[Category: Large Structures]]
[[Category: Harrop, S J.]]
[[Category: Cumi PMG]]
[[Category: Joss, T V.]]
[[Category: Harrop SJ]]
[[Category: Roberts, T H.]]
[[Category: Joss TV]]
[[Category: Apoplast]]
[[Category: Roberts TH]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Plant serpin serpin-zx arathzx serpin-1 atserpin1]]
[[Category: Protease inhibitor]]
[[Category: Secreted]]
[[Category: Serine protease inhibitor]]

Latest revision as of 10:20, 21 February 2024

Structure of Arabidopsis AtSerpin1. Native Stressed Conformation

3le2, resolution 2.20Å

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