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[[Image:3ql0.png|left|200px]]


{{STRUCTURE_3ql0|  PDB=3ql0  |  SCENE=  }}
==Crystal structure of N23PP/S148A mutant of E. coli dihydrofolate reductase==
 
<StructureSection load='3ql0' size='340' side='right'caption='[[3ql0]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
===Crystal structure of N23PP/S148A mutant of E. coli dihydrofolate reductase===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ql0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_UTI89 Escherichia coli UTI89]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QL0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QL0 FirstGlance]. <br>
{{ABSTRACT_PUBMED_21474759}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ql0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ql0 OCA], [https://pdbe.org/3ql0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ql0 RCSB], [https://www.ebi.ac.uk/pdbsum/3ql0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ql0 ProSAT]</span></td></tr>
[[3ql0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QL0 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q1RGF0_ECOUT Q1RGF0_ECOUT]


==See Also==
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021474759</ref><references group="xtra"/>
[[Category: Escherichia coli UTI89]]
[[Category: Dihydrofolate reductase]]
[[Category: Large Structures]]
[[Category: Escherichia coli]]
[[Category: Bhabha G]]
[[Category: Bhabha, G.]]
[[Category: Ekiert DC]]
[[Category: Ekiert, D C.]]
[[Category: Wilson IA]]
[[Category: Wilson, I A.]]
[[Category: Wright PE]]
[[Category: Wright, P E.]]
[[Category: Oxidoreductase]]
[[Category: Rossman fold]]
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