1wze: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus== | |||
<StructureSection load='1wze' size='340' side='right'caption='[[1wze]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1wze]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WZE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WZE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wze OCA], [https://pdbe.org/1wze PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wze RCSB], [https://www.ebi.ac.uk/pdbsum/1wze PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wze ProSAT]</span></td></tr> | ||
[[1wze]] is a 2 chain structure with sequence from [ | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/MDH_THETH MDH_THETH] Catalyzes the reversible oxidation of malate to oxaloacetate. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wz/1wze_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wze ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | ==See Also== | ||
*[[Malate Dehydrogenase 3D structures|Malate Dehydrogenase 3D structures]] | |||
*[[Malate | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: | |||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
[[Category: Fushinobu | [[Category: Fushinobu S]] | ||
[[Category: Kuzuyama | [[Category: Kuzuyama T]] | ||
[[Category: Nishiyama | [[Category: Nishiyama M]] | ||
[[Category: Tomita | [[Category: Tomita T]] | ||
Latest revision as of 08:02, 25 October 2023
Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus
| ||||||||||||
