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[[Image:1ogk.png|left|200px]]


{{STRUCTURE_1ogk|  PDB=1ogk  |  SCENE= }}
==The crystal structure of Trypanosoma cruzi dUTPase in complex with dUDP==
 
<StructureSection load='1ogk' size='340' side='right'caption='[[1ogk]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
===THE CRYSTAL STRUCTURE OF TRYPANOSOMA CRUZI DUTPASE IN COMPLEX WITH DUDP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1ogk]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OGK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OGK FirstGlance]. <br>
{{ABSTRACT_PUBMED_14725764}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DUD:DEOXYURIDINE-5-DIPHOSPHATE'>DUD</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ogk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ogk OCA], [https://pdbe.org/1ogk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ogk RCSB], [https://www.ebi.ac.uk/pdbsum/1ogk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ogk ProSAT]</span></td></tr>
[[1ogk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OGK OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/O15923_TRYCR O15923_TRYCR]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/og/1ogk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ogk ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase|Deoxyuridine 5'-triphosphate nucleotidohydrolase]]
*[[DUTPase 3D structures|DUTPase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:014725764</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
[[Category: DUTP diphosphatase]]
[[Category: Bernier-Villamor V]]
[[Category: Bernier-Villamor, V.]]
[[Category: Dodson EJ]]
[[Category: Dodson, E J.]]
[[Category: Gonzalez-Pacanowska D]]
[[Category: Gonzalez-Pacanowska, D.]]
[[Category: Harkiolaki M]]
[[Category: Harkiolaki, M.]]
[[Category: Turkenburg JP]]
[[Category: Turkenburg, J P.]]
[[Category: Wilson KS]]
[[Category: Wilson, K S.]]
[[Category: Dimer]]
[[Category: Hydrolase]]

Latest revision as of 05:47, 17 April 2024

The crystal structure of Trypanosoma cruzi dUTPase in complex with dUDP

1ogk, resolution 2.85Å

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