1d9c: Difference between revisions

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[[Image:1d9c.png|left|200px]]


{{STRUCTURE_1d9c|  PDB=1d9c  |  SCENE=  }}
==BOVINE INTERFERON-GAMMA AT 2.0 ANGSTROMS==
 
<StructureSection load='1d9c' size='340' side='right'caption='[[1d9c]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===BOVINE INTERFERON-GAMMA AT 2.0 ANGSTROMS===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1d9c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D9C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D9C FirstGlance]. <br>
{{ABSTRACT_PUBMED_10666622}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d9c OCA], [https://pdbe.org/1d9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d9c RCSB], [https://www.ebi.ac.uk/pdbsum/1d9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d9c ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1d9c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D9C OCA].  
== Function ==
[https://www.uniprot.org/uniprot/IFNG_BOVIN IFNG_BOVIN] Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d9/1d9c_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1d9c ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Interferon|Interferon]]
*[[Interferon 3D structures|Interferon 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010666622</ref><references group="xtra"/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Kossiakoff, A A.]]
[[Category: Large Structures]]
[[Category: Randal, M.]]
[[Category: Kossiakoff AA]]
[[Category: Helical homodimer]]
[[Category: Randal M]]
[[Category: Immune system]]
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