3ro4: Difference between revisions

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[[Image:3ro4.png|left|200px]]


{{STRUCTURE_3ro4|  PDB=3ro4  |  SCENE=  }}
==X-ray Structure of Ketohexokinase in complex with an indazole compound derivative==
 
<StructureSection load='3ro4' size='340' side='right'caption='[[3ro4]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
===X-ray Structure of Ketohexokinase in complex with an indazole compound derivative===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ro4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RO4 FirstGlance]. <br>
{{ABSTRACT_PUBMED_21767952}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LJ9:3-ETHYL-6-[(3AR,6AS)-HEXAHYDROPYRROLO[3,4-C]PYRROL-2(1H)-YL]-1-PHENYL-1H-INDAZOLE'>LJ9</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ro4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ro4 OCA], [https://pdbe.org/3ro4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ro4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ro4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ro4 ProSAT]</span></td></tr>
[[3ro4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RO4 OCA].  
</table>
== Disease ==
[https://www.uniprot.org/uniprot/KHK_HUMAN KHK_HUMAN] Defects in KHK are the cause of fructosuria (FRUCT) [MIM:[https://omim.org/entry/229800 229800]. Benign defect of intermediary metabolism.<ref>PMID:19237742</ref> <ref>PMID:7833921</ref>
== Function ==
[https://www.uniprot.org/uniprot/KHK_HUMAN KHK_HUMAN]


==See Also==
==See Also==
*[[Ketohexokinase|Ketohexokinase]]
*[[Ketohexokinase|Ketohexokinase]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:021767952</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ketohexokinase]]
[[Category: Large Structures]]
[[Category: Abad, M C.]]
[[Category: Abad MC]]
[[Category: Gibbs, A C.]]
[[Category: Gibbs AC]]
[[Category: Atp binding]]
[[Category: Kinase]]
[[Category: Transferase-transferase inhibitor complex]]
Retrieved from "https://proteopedia.org/3ro4"