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[[Image:1sqe.png|left|200px]]


{{STRUCTURE_1sqe|  PDB=1sqe  |  SCENE=  }}
==1.5A Crystal Structure Of the protein PG130 from Staphylococcus aureus, Structural genomics==
 
<StructureSection load='1sqe' size='340' side='right'caption='[[1sqe]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
===1.5A Crystal Structure Of the protein PG130 from Staphylococcus aureus, Structural genomics===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1sqe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SQE FirstGlance]. <br>
{{ABSTRACT_PUBMED_15520015}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sqe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sqe OCA], [https://pdbe.org/1sqe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sqe RCSB], [https://www.ebi.ac.uk/pdbsum/1sqe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sqe ProSAT], [https://www.topsan.org/Proteins/MCSG/1sqe TOPSAN]</span></td></tr>
==About this Structure==
</table>
[[1sqe]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQE OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/HDOX2_STAAM HDOX2_STAAM] Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.[HAMAP-Rule:MF_01272]
==See Also==
== Evolutionary Conservation ==
*[[IsdI|IsdI]]
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
==Reference==
  <jmolCheckbox>
<ref group="xtra">PMID:015520015</ref><references group="xtra"/>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sq/1sqe_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sqe ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak A]]
[[Category: Joachimiak, G.]]
[[Category: Joachimiak G]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Schneewind O]]
[[Category: Schneewind, O.]]
[[Category: Wu R]]
[[Category: Wu, R.]]
[[Category: Zhang R]]
[[Category: Zhang, R.]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Protein structure initiative]]
[[Category: Psi]]
[[Category: Structural genomic]]
[[Category: Unknown function]]
Retrieved from "https://proteopedia.org/1sqe"