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[[Image:3ler.png|left|200px]]


{{STRUCTURE_3ler|  PDB=3ler  |  SCENE=  }}
==Crystal Structure of Dihydrodipicolinate Synthase from Campylobacter jejuni subsp. jejuni NCTC 11168==
 
<StructureSection load='3ler' size='340' side='right'caption='[[3ler]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
===Crystal Structure of Dihydrodipicolinate Synthase from Campylobacter jejuni subsp. jejuni NCTC 11168===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ler]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_NCTC_11168_=_ATCC_700819 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LER FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.84&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=KPI:(2S)-2-AMINO-6-[(1-HYDROXY-1-OXO-PROPAN-2-YLIDENE)AMINO]HEXANOIC+ACID'>KPI</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
[[3ler]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni Campylobacter jejuni subsp. jejuni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LER OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ler FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ler OCA], [https://pdbe.org/3ler PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ler RCSB], [https://www.ebi.ac.uk/pdbsum/3ler PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ler ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DAPA_CAMJE DAPA_CAMJE] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[HAMAP-Rule:MF_00418]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/le/3ler_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ler ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Dihydrodipicolinate Synthase|Dihydrodipicolinate Synthase]]
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
[[Category: Campylobacter jejuni subsp. jejuni]]
__TOC__
[[Category: Dihydrodipicolinate synthase]]
</StructureSection>
[[Category: Anderson, W F.]]
[[Category: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Large Structures]]
[[Category: Hasseman, J.]]
[[Category: Anderson WF]]
[[Category: Joachimiak, A.]]
[[Category: Hasseman J]]
[[Category: Kim, Y.]]
[[Category: Joachimiak A]]
[[Category: Zhou, M.]]
[[Category: Kim Y]]
[[Category: Amino-acid biosynthesis]]
[[Category: Zhou M]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Diaminopimelate biosynthesis]]
[[Category: Lyase]]
[[Category: Lysine biosynthesis]]
[[Category: Schiff base]]
[[Category: Structural genomic]]
[[Category: Tim barrel]]
Retrieved from "https://proteopedia.org/3ler"