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[[Image:3rmb.png|left|200px]]


{{STRUCTURE_3rmb|  PDB=3rmb  |  SCENE=  }}
==Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol==
 
<StructureSection load='3rmb' size='340' side='right'caption='[[3rmb]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
===Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3rmb]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_RB69 Escherichia phage RB69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RMB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RMB FirstGlance]. <br>
{{ABSTRACT_PUBMED_21781974}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CTG:(5R,6S)-5,6-DIHYDRO-5,6-DIHYDROXYTHYMIDINE-5-MONOPHOSPHATE'>CTG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rmb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rmb OCA], [https://pdbe.org/3rmb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rmb RCSB], [https://www.ebi.ac.uk/pdbsum/3rmb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rmb ProSAT]</span></td></tr>
[[3rmb]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_rb69 Enterobacteria phage rb69]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RMB OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.


==See Also==
==See Also==
*[[DNA polymerase|DNA polymerase]]
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021781974</ref><ref group="xtra">PMID:017210917</ref><references group="xtra"/>
[[Category: Escherichia phage RB69]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Large Structures]]
[[Category: Enterobacteria phage rb69]]
[[Category: Aller P]]
[[Category: Aller, P.]]
[[Category: Doublie S]]
[[Category: Doublie, S.]]
[[Category: Duclos S]]
[[Category: Duclos, S.]]
[[Category: Wallace SS]]
[[Category: Wallace, S S.]]
[[Category: Dna lesion]]
[[Category: Protein-dna complex]]
[[Category: Thymine glycol]]
[[Category: Transferase-dna complex]]

Latest revision as of 12:29, 14 March 2024

Crystal Structure of a replicative DNA polymerase bound to DNA containing Thymine Glycol

3rmb, resolution 2.65Å

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