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[[Image:3l2x.png|left|200px]]


{{STRUCTURE_3l2x|  PDB=3l2x  |  SCENE=  }}
==Crystal Structure of Spin Labeled T4 Lysozyme Mutant 115-119RX==
 
<StructureSection load='3l2x' size='340' side='right'caption='[[3l2x]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Crystal Structure of Spin Labeled T4 Lysozyme Mutant 115-119RX===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3l2x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L2X FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene>, <scene name='pdbligand=RXR:[2,2,5,5-TETRAMETHYL-3,4-BIS(SULFANYLMETHYL)-2,5-DIHYDRO-1H-PYRROL-1-YL]OXIDANYL+RADICAL'>RXR</scene></td></tr>
[[3l2x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L2X OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l2x OCA], [https://pdbe.org/3l2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l2x RCSB], [https://www.ebi.ac.uk/pdbsum/3l2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l2x ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>


==See Also==
==See Also==
*[[Hen Egg-White (HEW) Lysozyme|Hen Egg-White (HEW) Lysozyme]]
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
[[Category: Enterobacteria phage t4]]
== References ==
[[Category: Lysozyme]]
<references/>
[[Category: Cascio, D.]]
__TOC__
[[Category: Fleissner, M R.]]
</StructureSection>
[[Category: Hubbell, W L.]]
[[Category: Escherichia virus T4]]
[[Category: Antimicrobial]]
[[Category: Large Structures]]
[[Category: Bacteriolytic enzyme]]
[[Category: Cascio D]]
[[Category: Epr]]
[[Category: Fleissner MR]]
[[Category: Glycosidase]]
[[Category: Hubbell WL]]
[[Category: Hydrolase]]
[[Category: Modified cysteine]]
[[Category: Nitroxide spin label]]

Latest revision as of 06:35, 19 July 2023

Crystal Structure of Spin Labeled T4 Lysozyme Mutant 115-119RX

3l2x, resolution 1.80Å

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