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[[Image:3psf.png|left|200px]]


{{STRUCTURE_3psf|  PDB=3psf  |  SCENE=  }}
==Crystal Structure of the Spt6 core domain from Saccharomyces cerevisiae, Form Spt6(236-1259)==
 
<StructureSection load='3psf' size='340' side='right'caption='[[3psf]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
===Crystal Structure of the Spt6 core domain from Saccharomyces cerevisiae, Form Spt6(236-1259)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3psf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PSF FirstGlance]. <br>
{{ABSTRACT_PUBMED_21419780}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3psf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3psf OCA], [https://pdbe.org/3psf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3psf RCSB], [https://www.ebi.ac.uk/pdbsum/3psf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3psf ProSAT]</span></td></tr>
==About this Structure==
</table>
[[3psf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSF OCA].  
== Function ==
[https://www.uniprot.org/uniprot/SPT6_YEAST SPT6_YEAST] Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression. Essential for viability.<ref>PMID:9450930</ref> <ref>PMID:12934008</ref> <ref>PMID:15531585</ref> <ref>PMID:16455495</ref>


==See Also==
==See Also==
*[[Elongation factor|Elongation factor]]
*[[Elongation factor 3D structures|Elongation factor 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:021419780</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Close, D.]]
[[Category: Close D]]
[[Category: Hill, C P.]]
[[Category: Hill CP]]
[[Category: Nucleus]]
[[Category: Transcription]]
[[Category: Transcription elongation]]

Latest revision as of 10:43, 21 February 2024

Crystal Structure of the Spt6 core domain from Saccharomyces cerevisiae, Form Spt6(236-1259)

3psf, resolution 2.59Å

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