1c9b: Difference between revisions

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[[Image:1c9b.png|left|200px]]


{{STRUCTURE_1c9b|  PDB=1c9b  |  SCENE=  }}
==CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)==
 
<StructureSection load='1c9b' size='340' side='right'caption='[[1c9b]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
===CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1c9b]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C9B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C9B FirstGlance]. <br>
{{ABSTRACT_PUBMED_10619841}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c9b OCA], [https://pdbe.org/1c9b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c9b RCSB], [https://www.ebi.ac.uk/pdbsum/1c9b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c9b ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1c9b]] is a 20 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C9B OCA].  
== Function ==
[https://www.uniprot.org/uniprot/TF2B_HUMAN TF2B_HUMAN] General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/1c9b_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c9b ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[TATA-Binding Protein|TATA-Binding Protein]]
*[[TATA-binding protein 3D structures|TATA-binding protein 3D structures]]
*[[Transcription initiation factor|Transcription initiation factor]]
*[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010619841</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Sigler, P B.]]
[[Category: Large Structures]]
[[Category: Tsai, F T.F.]]
[[Category: Sigler PB]]
[[Category: Cyclin-like fold]]
[[Category: Tsai FTF]]
[[Category: Helix-turn-helix]]
[[Category: Protein-dna complex]]
[[Category: Tata-box]]
[[Category: Transcription-dna complex]]
Retrieved from "https://proteopedia.org/1c9b"