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[[Image:1sek.png|left|200px]]


{{STRUCTURE_1sek|  PDB=1sek  |  SCENE=  }}
==THE STRUCTURE OF ACTIVE SERPIN K FROM MANDUCA SEXTA AND A MODEL FOR SERPIN-PROTEASE COMPLEX FORMATION==
 
<StructureSection load='1sek' size='340' side='right'caption='[[1sek]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===THE STRUCTURE OF ACTIVE SERPIN K FROM MANDUCA SEXTA AND A MODEL FOR SERPIN-PROTEASE COMPLEX FORMATION===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1sek]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Manduca_sexta Manduca sexta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SEK FirstGlance]. <br>
{{ABSTRACT_PUBMED_10368276}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sek OCA], [https://pdbe.org/1sek PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sek RCSB], [https://www.ebi.ac.uk/pdbsum/1sek PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sek ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1sek]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Manduca_sexta Manduca sexta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEK OCA].  
== Function ==
[https://www.uniprot.org/uniprot/Q25526_MANSE Q25526_MANSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/se/1sek_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sek ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Serpin|Serpin]]
*[[Serpin 3D structures|Serpin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010368276</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Manduca sexta]]
[[Category: Manduca sexta]]
[[Category: Canagarajah, B.]]
[[Category: Canagarajah B]]
[[Category: Goldsmith, E J.]]
[[Category: Goldsmith EJ]]
[[Category: Jiang, H.]]
[[Category: Jiang H]]
[[Category: Kanost, M.]]
[[Category: Kanost M]]
[[Category: Li, J.]]
[[Category: Li J]]
[[Category: Wang, Z.]]
[[Category: Wang Z]]
[[Category: Protease]]
[[Category: Serine protease inhibitor]]
[[Category: Serpin]]