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[[Image:2kxw.png|left|200px]]


{{STRUCTURE_2kxw|  PDB=2kxw  |  SCENE=  }}
==Structure of the C-domain Fragment of apo Calmodulin Bound to the IQ motif of Nav1.2==
 
<StructureSection load='2kxw' size='340' side='right'caption='[[2kxw]]' scene=''>
===Structure of the C-domain Fragment of apo Calmodulin Bound to the IQ motif of Nav1.2===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2kxw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Paramecium_tetraurelia Paramecium tetraurelia] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KXW FirstGlance]. <br>
{{ABSTRACT_PUBMED_21439835}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kxw OCA], [https://pdbe.org/2kxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kxw RCSB], [https://www.ebi.ac.uk/pdbsum/2kxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kxw ProSAT]</span></td></tr>
==About this Structure==
</table>
[[2kxw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Paramecium_tetraurelia Paramecium tetraurelia]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KXW OCA].  
== Function ==
[https://www.uniprot.org/uniprot/CALM_PARTE CALM_PARTE] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.


==See Also==
==See Also==
*[[Calmodulin|Calmodulin]]
*[[Calmodulin 3D structures|Calmodulin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021439835</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Paramecium tetraurelia]]
[[Category: Paramecium tetraurelia]]
[[Category: Feldkamp, M D.]]
[[Category: Rattus norvegicus]]
[[Category: Shea, M A.]]
[[Category: Feldkamp MD]]
[[Category: Yu, L.]]
[[Category: Shea MA]]
[[Category: Action potential]]
[[Category: Yu L]]
[[Category: Amino acid motif]]
[[Category: Animal]]
[[Category: Autism]]
[[Category: Biomolecular]]
[[Category: Brain chemistry]]
[[Category: Calcium-binding protein-metal transport complex]]
[[Category: Calcium-binding protein]]
[[Category: Calmodulin]]
[[Category: Channel]]
[[Category: Glutamine]]
[[Category: Human]]
[[Category: Ion channel gating]]
[[Category: Iq motif]]
[[Category: Isoleucine]]
[[Category: Metal transport]]
[[Category: Model]]
[[Category: Molecular]]
[[Category: Nav1 2]]
[[Category: Neuronal]]
[[Category: Peptide]]
[[Category: Protein binding]]
[[Category: Protein structure]]
[[Category: Sodium channel]]
[[Category: Tertiary]]
[[Category: Tyrosine]]
[[Category: Voltage gated]]
[[Category: Voltage-dependent]]