3tew: Difference between revisions

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[[Image:3tew.png|left|200px]]


{{STRUCTURE_3tew|  PDB=3tew  |  SCENE=  }}
==Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.45-A resolution==
 
<StructureSection load='3tew' size='340' side='right'caption='[[3tew]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
===Crystal Structure of Anthrax Protective Antigen (Membrane Insertion Loop Deleted) to 1.45-A resolution===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3tew]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TEW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TEW FirstGlance]. <br>
{{ABSTRACT_PUBMED_22063095}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MXE:2-METHOXYETHANOL'>MXE</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tew FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tew OCA], [https://pdbe.org/3tew PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tew RCSB], [https://www.ebi.ac.uk/pdbsum/3tew PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tew ProSAT]</span></td></tr>
[[3tew]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TEW OCA].  
</table>
 
== Function ==
==See Also==
[https://www.uniprot.org/uniprot/PAG_BACAN PAG_BACAN] One of the three proteins composing the anthrax toxin, the agent which infects many mammalian species and that may cause death. PA binds to a receptor (ATR) in sensitive eukaryotic cells, thereby facilitating the translocation of the enzymatic toxin components, edema factor and lethal factor, across the target cell membrane. PA associated with LF causes death when injected, PA associated with EF produces edema. PA induces immunity to infection with anthrax.
*[[Anthrax protective antigen|Anthrax protective antigen]]
__TOC__
 
</StructureSection>
==Reference==
<ref group="xtra">PMID:022063095</ref><references group="xtra"/>
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
[[Category: Feld, G K.]]
[[Category: Large Structures]]
[[Category: Krantz, B A.]]
[[Category: Feld GK]]
[[Category: Protein transport]]
[[Category: Krantz BA]]
[[Category: Toxin]]
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