1g06: Difference between revisions

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[[Image:1g06.png|left|200px]]


{{STRUCTURE_1g06|  PDB=1g06  |  SCENE=  }}
==CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT V149S==
 
<StructureSection load='1g06' size='340' side='right'caption='[[1g06]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
===CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT V149S===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1g06]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G06 FirstGlance]. <br>
{{ABSTRACT_PUBMED_11316887}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HED:2-HYDROXYETHYL+DISULFIDE'>HED</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g06 OCA], [https://pdbe.org/1g06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g06 RCSB], [https://www.ebi.ac.uk/pdbsum/1g06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g06 ProSAT]</span></td></tr>
[[1g06]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G06 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/1g06_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g06 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Hen Egg-White (HEW) Lysozyme|Hen Egg-White (HEW) Lysozyme]]
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:011316887</ref><references group="xtra"/>
__TOC__
[[Category: Enterobacteria phage t4]]
</StructureSection>
[[Category: Lysozyme]]
[[Category: Escherichia virus T4]]
[[Category: Baase, W A.]]
[[Category: Large Structures]]
[[Category: Matthews, B W.]]
[[Category: Baase WA]]
[[Category: Quillin, M L.]]
[[Category: Matthews BW]]
[[Category: Xu, J.]]
[[Category: Quillin ML]]
[[Category: Bacteriolytic enzyme]]
[[Category: Xu J]]
[[Category: Glycosidase]]
[[Category: Hydrolase]]
[[Category: O-glycosyl]]
Retrieved from "https://proteopedia.org/1g06"