1brj: Difference between revisions

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[[Image:1brj.png|left|200px]]


{{STRUCTURE_1brj|  PDB=1brj  |  SCENE=  }}
==BARNASE MUTANT WITH ILE 88 REPLACED BY ALA==
 
<StructureSection load='1brj' size='340' side='right'caption='[[1brj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===BARNASE MUTANT WITH ILE 88 REPLACED BY ALA===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1brj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BRJ FirstGlance]. <br>
{{ABSTRACT_PUBMED_8605178}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1brj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1brj OCA], [https://pdbe.org/1brj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1brj RCSB], [https://www.ebi.ac.uk/pdbsum/1brj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1brj ProSAT]</span></td></tr>
[[1brj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRJ OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/RNBR_BACAM RNBR_BACAM] Hydrolyzes phosphodiester bonds in RNA, poly- and oligoribonucleotides resulting in 3'-nucleoside monophosphates via 2',3'-cyclophosphate intermediates.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/1brj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1brj ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Barnase|Barnase]]
*[[Barnase 3D structures|Barnase 3D structures]]
*[[Ribonuclease|Ribonuclease]]
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:008605178</ref><references group="xtra"/>
[[Category: Bacillus amyloliquefaciens]]
[[Category: Bacillus amyloliquefaciens]]
[[Category: Buckle, A.]]
[[Category: Large Structures]]
[[Category: Cramer, P C.]]
[[Category: Buckle A]]
[[Category: Fersht, A.]]
[[Category: Cramer PC]]
[[Category: Alpha/beta protein]]
[[Category: Fersht A]]
[[Category: Endonuclease]]

Latest revision as of 06:38, 7 February 2024

BARNASE MUTANT WITH ILE 88 REPLACED BY ALA

1brj, resolution 2.00Å

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