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[[Image:3q1h.png|left|200px]]


{{STRUCTURE_3q1h|  PDB=3q1h  |  SCENE=  }}
==Crystal Structure of Dihydrofolate Reductase from Yersinia pestis==
 
<StructureSection load='3q1h' size='340' side='right'caption='[[3q1h]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Crystal Structure of Dihydrofolate Reductase from Yersinia pestis===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3q1h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_CO92 Yersinia pestis CO92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q1H FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.804&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[3q1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q1H OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q1h OCA], [https://pdbe.org/3q1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q1h RCSB], [https://www.ebi.ac.uk/pdbsum/3q1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q1h ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A3N4BLI0_YERPE A0A3N4BLI0_YERPE] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[ARBA:ARBA00025067][PIRNR:PIRNR000194]


==See Also==
==See Also==
*[[Dihydrofolate reductase|Dihydrofolate reductase]]
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
[[Category: Dihydrofolate reductase]]
__TOC__
[[Category: Yersinia pestis]]
</StructureSection>
[[Category: Anderson, W F.]]
[[Category: Large Structures]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Yersinia pestis CO92]]
[[Category: Joachimiak, A.]]
[[Category: Anderson WF]]
[[Category: Kim, Y.]]
[[Category: Joachimiak A]]
[[Category: Makowska-Grzyska, M.]]
[[Category: Kim Y]]
[[Category: Maltseva, N.]]
[[Category: Makowska-Grzyska M]]
[[Category: Mulligan, R.]]
[[Category: Maltseva N]]
[[Category: Papazisi, L.]]
[[Category: Mulligan R]]
[[Category: Alpha beta fold]]
[[Category: Papazisi L]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Cytosol]]
[[Category: Oxidoreductase]]
[[Category: Structural genomic]]

Latest revision as of 11:29, 14 March 2024

Crystal Structure of Dihydrofolate Reductase from Yersinia pestis

3q1h, resolution 1.80Å

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