2xok: Difference between revisions

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[[Image:2xok.png|left|200px]]


{{STRUCTURE_2xok| PDB=2xok | SCENE= }}
==Refined structure of yeast F1c10 ATPase complex to 3 A resolution==
<StructureSection load='2xok' size='340' side='right'caption='[[2xok]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2xok]] is a 19 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XOK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XOK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.01&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xok OCA], [https://pdbe.org/2xok PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xok RCSB], [https://www.ebi.ac.uk/pdbsum/2xok PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xok ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/E9P9X4_YEASX E9P9X4_YEASX]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xo/2xok_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xok ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Adenosine triphosphate (ATP) synthase contains a rotary motor involved in biological energy conversion. Its membrane-embedded F0 sector has a rotation generator fueled by the proton-motive force, which provides the energy required for the synthesis of ATP by the F1 domain. An electron density map obtained from crystals of a subcomplex of yeast mitochondrial ATP synthase shows a ring of 10 c subunits. Each c subunit forms an alpha-helical hairpin. The interhelical loops of six to seven of the c subunits are in close contact with the gamma and delta subunits of the central stalk. The extensive contact between the c ring and the stalk suggests that they may rotate as an ensemble during catalysis.


===REFINED STRUCTURE OF YEAST F1C10 ATPASE COMPLEX TO 3 A RESOLUTION===
Molecular architecture of the rotary motor in ATP synthase.,Stock D, Leslie AG, Walker JE Science. 1999 Nov 26;286(5445):1700-5. PMID:10576729<ref>PMID:10576729</ref>


{{ABSTRACT_PUBMED_10576729}}
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
</div>
==About this Structure==
<div class="pdbe-citations 2xok" style="background-color:#fffaf0;"></div>
[[2xok]] is a 19 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XOK OCA].


==See Also==
==See Also==
*[[ATP synthase|ATP synthase]]
*[[ATPase 3D structures|ATPase 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:010576729</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Leslie, A G.W.]]
[[Category: Stock D]]
[[Category: Stock, D.]]
[[Category: W Leslie AG]]
[[Category: Walker, J E.]]
[[Category: Walker JE]]
[[Category: Atp synthase]]
[[Category: Atp-binding]]
[[Category: Hydrolase]]
[[Category: Inner membrane]]
[[Category: Mitochondria]]
[[Category: Transmembrane]]