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[[Image:1bg2.png|left|200px]]


{{STRUCTURE_1bg2|  PDB=1bg2  |  SCENE=  }}
==HUMAN UBIQUITOUS KINESIN MOTOR DOMAIN==
 
<StructureSection load='1bg2' size='340' side='right'caption='[[1bg2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===HUMAN UBIQUITOUS KINESIN MOTOR DOMAIN===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1bg2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The April 2005 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Kinesin''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2005_4 10.2210/rcsb_pdb/mom_2005_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BG2 FirstGlance]. <br>
{{ABSTRACT_PUBMED_8606779}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bg2 OCA], [https://pdbe.org/1bg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bg2 RCSB], [https://www.ebi.ac.uk/pdbsum/1bg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bg2 ProSAT]</span></td></tr>
[[1bg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The April 2005 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Kinesin''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2005_4 10.2210/rcsb_pdb/mom_2005_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BG2 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/KINH_HUMAN KINH_HUMAN] Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bg/1bg2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bg2 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Kinesin|Kinesin]]
*[[Kinesin 3D Structures|Kinesin 3D Structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:008606779</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kinesin]]
[[Category: Kinesin]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Fletterick, R J.]]
[[Category: Fletterick RJ]]
[[Category: Kull, F J.]]
[[Category: Kull FJ]]
[[Category: Lau, R.]]
[[Category: Lau R]]
[[Category: Sablin, E P.]]
[[Category: Sablin EP]]
[[Category: Vale, R D.]]
[[Category: Vale RD]]
[[Category: Atpase]]
[[Category: Microtubule associated]]
[[Category: Motor protein]]
Retrieved from "https://proteopedia.org/1bg2"