2a12: Difference between revisions
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{{Theoretical_model}} | {{Theoretical_model}} | ||
[[ | ==THEORETICAL MODEL OF THE AI5G GROUP II INTRON== | ||
<StructureSection load='2a12' size='340' side='right'caption='[[2a12]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A12 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a12 FirstGlance], [https://www.ebi.ac.uk/pdbsum/2a12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a12 ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Despite the biological importance of self-splicing group II introns, little is known about their structural organization. Synthetic incorporation of site-specific photo-cross-linkers within catalytic domains resulted in functional distance constraints that, when combined with known tertiary interactions, provide a three-dimensional view of the active intron architecture. All functionalities important for both steps of splicing are proximal before the first step, suggestive of a single active-site region for group II intron catalysis. | |||
A single active-site region for a group II intron.,de Lencastre A, Hamill S, Pyle AM Nat Struct Mol Biol. 2005 Jul;12(7):626-7. Epub 2005 Jun 26. PMID:15980867<ref>PMID:15980867</ref> | |||
== | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | |||
<div class="pdbe-citations 2a12" style="background-color:#fffaf0;"></div> | |||
== References == | |||
== | <references/> | ||
< | __TOC__ | ||
</StructureSection> | |||
[[Category: Theoretical Model]] | |||
[[Category: Large Structures]] | |||
[[Category: De Lencastre, A]] | [[Category: De Lencastre, A]] | ||
[[Category: Hamill, S]] | [[Category: Hamill, S]] | ||
[[Category: Pyle, A M]] | [[Category: Pyle, A M]] | ||
Latest revision as of 14:34, 17 November 2021
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THEORETICAL MODEL OF THE AI5G GROUP II INTRON
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