2k1p: Difference between revisions

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[[Image:2k1p.png|left|200px]]


{{STRUCTURE_2k1p|  PDB=2k1p  |  SCENE=  }}
==Solution structure of the second zinc finger domain of ZRANB2/ZNF265==
 
<StructureSection load='2k1p' size='340' side='right'caption='[[2k1p]]' scene=''>
===Solution structure of the second zinc finger domain of ZRANB2/ZNF265===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2k1p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K1P FirstGlance]. <br>
{{ABSTRACT_PUBMED_019304800}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k1p OCA], [https://pdbe.org/2k1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k1p RCSB], [https://www.ebi.ac.uk/pdbsum/2k1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k1p ProSAT]</span></td></tr>
[[2k1p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K1P OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/ZRAB2_HUMAN ZRAB2_HUMAN] Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.<ref>PMID:11448987</ref>  
<ref group="xtra">PMID:019304800</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k1/2k1p_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k1p ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Loughlin, F E.]]
[[Category: Large Structures]]
[[Category: Mackay, J P.]]
[[Category: Loughlin FE]]
[[Category: Metal-binding]]
[[Category: Mackay JP]]
[[Category: Mrna processing]]
[[Category: Mrna splicing]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Ranbp2]]
[[Category: Rbz]]
[[Category: Rna binding]]
[[Category: Rna-binding]]
[[Category: Transcription]]
[[Category: Zinc finger]]
[[Category: Zinc-finger]]
[[Category: Zi]]
[[Category: Znf265]]

Latest revision as of 06:43, 1 May 2024

Solution structure of the second zinc finger domain of ZRANB2/ZNF265

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