1a17: Difference between revisions

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[[Image:1a17.png|left|200px]]


{{STRUCTURE_1a17|  PDB=1a17  |  SCENE=  }}
==TETRATRICOPEPTIDE REPEATS OF PROTEIN PHOSPHATASE 5==
 
<StructureSection load='1a17' size='340' side='right'caption='[[1a17]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
===TETRATRICOPEPTIDE REPEATS OF PROTEIN PHOSPHATASE 5===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1a17]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A17 FirstGlance]. <br>
{{ABSTRACT_PUBMED_9482716}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a17 OCA], [https://pdbe.org/1a17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a17 RCSB], [https://www.ebi.ac.uk/pdbsum/1a17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a17 ProSAT]</span></td></tr>
[[1a17]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A17 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/PPP5_HUMAN PPP5_HUMAN] May play a role in the regulation of RNA biogenesis and/or mitosis. In vitro, dephosphorylates serine residues of skeletal muscle phosphorylase and histone H1.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/1a17_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1a17 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Serine/threonine protein phosphatase|Serine/threonine protein phosphatase]]
*[[Protein phosphatase 3D structures|Protein phosphatase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:009482716</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphoprotein phosphatase]]
[[Category: Large Structures]]
[[Category: Barford, D.]]
[[Category: Barford D]]
[[Category: Cohen, P T.W.]]
[[Category: Cohen PTW]]
[[Category: Das, A K.]]
[[Category: Das AK]]
[[Category: Hydrolase]]
[[Category: Phosphatase]]
[[Category: Protein-protein interaction]]
[[Category: Super-helix]]
[[Category: Tpr]]