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[[Image:1bb9.png|left|200px]]


{{STRUCTURE_1bb9|  PDB=1bb9  |  SCENE=  }}
==CRYSTAL STRUCTURE OF THE SH3 DOMAIN FROM RAT AMPHIPHYSIN 2==
 
<StructureSection load='1bb9' size='340' side='right'caption='[[1bb9]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===CRYSTAL STRUCTURE OF THE SH3 DOMAIN FROM RAT AMPHIPHYSIN 2===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1bb9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BB9 FirstGlance]. <br>
{{ABSTRACT_PUBMED_9736607}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bb9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bb9 OCA], [https://pdbe.org/1bb9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bb9 RCSB], [https://www.ebi.ac.uk/pdbsum/1bb9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bb9 ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1bb9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BB9 OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/BIN1_RAT BIN1_RAT] May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation.<ref>PMID:9736607</ref>  
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:009736607</ref><ref group="xtra">PMID:016446784</ref><ref group="xtra">PMID:019113835</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/1bb9_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bb9 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Evans, P R.]]
[[Category: Evans PR]]
[[Category: Mcmahon, H T.]]
[[Category: Mcmahon HT]]
[[Category: Owen, D J.]]
[[Category: Owen DJ]]
[[Category: Sh3 domain]]
[[Category: Transferase]]

Latest revision as of 06:34, 7 February 2024

CRYSTAL STRUCTURE OF THE SH3 DOMAIN FROM RAT AMPHIPHYSIN 2

1bb9, resolution 2.20Å

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