1c1k: Difference between revisions

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[[Image:1c1k.png|left|200px]]


{{STRUCTURE_1c1k|  PDB=1c1k  |  SCENE=  }}
==BACTERIOPHAGE T4 GENE 59 HELICASE ASSEMBLY PROTEIN==
 
<StructureSection load='1c1k' size='340' side='right'caption='[[1c1k]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
===BACTERIOPHAGE T4 GENE 59 HELICASE ASSEMBLY PROTEIN===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1c1k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C1K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C1K FirstGlance]. <br>
{{ABSTRACT_PUBMED_10669611}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IR:IRIDIUM+ION'>IR</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c1k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c1k OCA], [https://pdbe.org/1c1k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c1k RCSB], [https://www.ebi.ac.uk/pdbsum/1c1k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c1k ProSAT]</span></td></tr>
[[1c1k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C1K OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/HLOAD_BPT4 HLOAD_BPT4] DNA helicase loader protein that participates in viral DNA replication, recombination, and repair (PubMed:10871615). At the fork, required for loading of the replicative helicase onto DNA protected by the ssDNA-binding protein (PubMed:11459967, PubMed:7806533, PubMed:10871615, PubMed:22427673). Coordinates simultaneous synthesis of leading- and lagging-strands (PubMed:11459969).[HAMAP-Rule:MF_04156]<ref>PMID:10871615</ref> <ref>PMID:11459967</ref> <ref>PMID:22427673</ref> <ref>PMID:7806533</ref> <ref>PMID:11459969</ref>
<ref group="xtra">PMID:010669611</ref><ref group="xtra">PMID:014695246</ref><ref group="xtra">PMID:015048824</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Enterobacteria phage t4]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Hyde, C C.]]
Check<jmol>
[[Category: Jones, C E.]]
  <jmolCheckbox>
[[Category: Mueser, T C.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c1/1c1k_consurf.spt"</scriptWhenChecked>
[[Category: Nossal, N G.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Dna binding protein]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Dna recombination]]
  </jmolCheckbox>
[[Category: Dna replication]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c1k ConSurf].
[[Category: Forked dna]]
<div style="clear:both"></div>
[[Category: Helicase assembly]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia virus T4]]
[[Category: Large Structures]]
[[Category: Hyde CC]]
[[Category: Jones CE]]
[[Category: Mueser TC]]
[[Category: Nossal NG]]