1bw9: Difference between revisions

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[[Image:1bw9.png|left|200px]]


{{STRUCTURE_1bw9|  PDB=1bw9  |  SCENE=  }}
==PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND PHENYLPYRUVATE==
 
<StructureSection load='1bw9' size='340' side='right'caption='[[1bw9]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
===PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND PHENYLPYRUVATE===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1bw9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BW9 FirstGlance]. <br>
{{ABSTRACT_PUBMED_10029526}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=PPY:3-PHENYLPYRUVIC+ACID'>PPY</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bw9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bw9 OCA], [https://pdbe.org/1bw9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bw9 RCSB], [https://www.ebi.ac.uk/pdbsum/1bw9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bw9 ProSAT]</span></td></tr>
[[1bw9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp. Rhodococcus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BW9 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/DHPH_RHOSO DHPH_RHOSO] Catalyzes the reversible NAD(+)-dependent oxidative deamination of L-phenylalanine to phenylpyruvate.<ref>PMID:10924111</ref> <ref>PMID:8206922</ref>
<ref group="xtra">PMID:010029526</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Phenylalanine dehydrogenase]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Rhodococcus sp.]]
Check<jmol>
[[Category: Blanchard, J L.]]
  <jmolCheckbox>
[[Category: Brunhuber, N M.W.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bw/1bw9_consurf.spt"</scriptWhenChecked>
[[Category: Holden, H M.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Thoden, J B.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Vanhooke, J L.]]
  </jmolCheckbox>
[[Category: Amino acid dehydrogenase]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bw9 ConSurf].
[[Category: Oxidative deamination mechanism]]
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rhodococcus sp]]
[[Category: Blanchard JL]]
[[Category: Brunhuber NMW]]
[[Category: Holden HM]]
[[Category: Thoden JB]]
[[Category: Vanhooke JL]]

Latest revision as of 06:39, 7 February 2024

PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND PHENYLPYRUVATE

1bw9, resolution 1.50Å

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