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[[Image:1cdh.png|left|200px]]


{{STRUCTURE_1cdh| PDB=1cdh | SCENE= }}
==STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES==
<StructureSection load='1cdh' size='340' side='right'caption='[[1cdh]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1cdh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1cd4 1cd4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CDH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CDH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cdh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cdh OCA], [https://pdbe.org/1cdh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cdh RCSB], [https://www.ebi.ac.uk/pdbsum/1cdh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cdh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cd/1cdh_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cdh ConSurf].
<div style="clear:both"></div>


===STRUCTURES OF AN HIV AND MHC BINDING FRAGMENT FROM HUMAN CD4 AS REFINED IN TWO CRYSTAL LATTICES===
==See Also==
 
*[[CD4 3D structures|CD4 3D structures]]
{{ABSTRACT_PUBMED_8075984}}
__TOC__
 
</StructureSection>
==About this Structure==
[[1cdh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1cd4 1cd4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CDH OCA].
 
==Reference==
<ref group="xtra">PMID:008075984</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hendrickson, W A.]]
[[Category: Large Structures]]
[[Category: Ryu, S E.]]
[[Category: Hendrickson WA]]
[[Category: Sweet, R W.]]
[[Category: Ryu SE]]
[[Category: Truneh, A.]]
[[Category: Sweet RW]]
[[Category: T-cell surface glycoprotein]]
[[Category: Truneh A]]
Retrieved from "https://proteopedia.org/1cdh"