1p0g: Difference between revisions

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[[Image:1p0g.gif|left|200px]]<br /><applet load="1p0g" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1p0g" />
'''Structure of Antimicrobial Peptide, HP (2-20) and its Analogues Derived from Helicobacter pylori, as Determined by 1H NMR Spectroscopy'''<br />


==About this Structure==
==Structure of Antimicrobial Peptide, HP (2-20) and its Analogues Derived from Helicobacter pylori, as Determined by 1H NMR Spectroscopy==
1P0G is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0G OCA].  
<StructureSection load='1p0g' size='340' side='right'caption='[[1p0g]]' scene=''>
[[Category: Single protein]]
== Structural highlights ==
[[Category: Harm, K S.]]
<table><tr><td colspan='2'>[[1p0g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_J99 Helicobacter pylori J99]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P0G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P0G FirstGlance]. <br>
[[Category: Kim, Y M.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
[[Category: Lee, D G.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
[[Category: Lee, K H.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p0g OCA], [https://pdbe.org/1p0g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p0g RCSB], [https://www.ebi.ac.uk/pdbsum/1p0g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p0g ProSAT]</span></td></tr>
[[Category: Park, Y K.]]
</table>
[[Category: NH2]]
== Function ==
[[Category: coil-helix-coil]]
[https://www.uniprot.org/uniprot/RL1_HELPY RL1_HELPY] Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity).[HAMAP-Rule:MF_01318]  Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA (By similarity).[HAMAP-Rule:MF_01318] Peptides originating from the N-terminal end of L1 have antibacterial activity against bacteria such as E.coli and B.megaterium and modest antifungal activities. Has no effect on H.pylori itself. Peptides are not hemolytic against mammalian cells. These peptides may be released in the stomach during altruistic lysis to kill other fast growing bacteria.[HAMAP-Rule:MF_01318]
 
__TOC__
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:23:40 2008''
</StructureSection>
[[Category: Helicobacter pylori J99]]
[[Category: Large Structures]]
[[Category: Harm KS]]
[[Category: Kim YM]]
[[Category: Lee DG]]
[[Category: Lee KH]]
[[Category: Park YK]]
Retrieved from "https://proteopedia.org/1p0g"