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[[Image:1dof.png|left|200px]]


{{STRUCTURE_1dof| PDB=1dof | SCENE= }}
==THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY==
<StructureSection load='1dof' size='340' side='right'caption='[[1dof]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1dof]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrobaculum_aerophilum Pyrobaculum aerophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DOF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dof OCA], [https://pdbe.org/1dof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dof RCSB], [https://www.ebi.ac.uk/pdbsum/1dof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dof ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8ZY28_PYRAE Q8ZY28_PYRAE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/do/1dof_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dof ConSurf].
<div style="clear:both"></div>


===THE CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM PYROBACULUM AEROPHILUM: INSIGHTS INTO THERMAL STABILITY AND HUMAN PATHOLOGY===
==See Also==
 
*[[Adenylosuccinate lyase 3D structures|Adenylosuccinate lyase 3D structures]]
{{ABSTRACT_PUBMED_10926519}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[1dof]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrobaculum_aerophilum Pyrobaculum aerophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DOF OCA].
 
==Reference==
<ref group="xtra">PMID:010926519</ref><references group="xtra"/>
[[Category: Adenylosuccinate lyase]]
[[Category: Pyrobaculum aerophilum]]
[[Category: Pyrobaculum aerophilum]]
[[Category: Dixon, J E.]]
[[Category: Dixon JE]]
[[Category: Goedken, E.]]
[[Category: Goedken E]]
[[Category: Marqusee, S.]]
[[Category: Marqusee S]]
[[Category: Toth, E A.]]
[[Category: Toth EA]]
[[Category: Yeates, T O.]]
[[Category: Yeates TO]]
[[Category: Lyase]]
[[Category: Purine biosynthesis]]