1e5g: Difference between revisions

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[[Image:1e5g.png|left|200px]]


{{STRUCTURE_1e5g|  PDB=1e5g  |  SCENE= }}
==Solution structure of central CP module pair of a pox virus complement inhibitor==
 
<StructureSection load='1e5g' size='340' side='right'caption='[[1e5g]]' scene=''>
===SOLUTION STRUCTURE OF CENTRAL CP MODULE PAIR OF A POX VIRUS COMPLEMENT INHIBITOR===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1e5g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Copenhagen Vaccinia virus Copenhagen]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E5G FirstGlance]. <br>
{{ABSTRACT_PUBMED_11243823}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e5g OCA], [https://pdbe.org/1e5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e5g RCSB], [https://www.ebi.ac.uk/pdbsum/1e5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e5g ProSAT]</span></td></tr>
==About this Structure==
</table>
[[1e5g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5G OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/VCP_VACCC VCP_VACCC] Serves to protect the virus against complement attack by inhibiting both classical and alternative pathways of complement activation. Binds C3b and C4b.
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:011243823</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Vaccinia virus]]
Check<jmol>
[[Category: Barlow, P N.]]
  <jmolCheckbox>
[[Category: Bromek, K.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e5/1e5g_consurf.spt"</scriptWhenChecked>
[[Category: Henderson, C E.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Mullin, N P.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Smith, B O.]]
  </jmolCheckbox>
[[Category: Uhrin, D.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e5g ConSurf].
[[Category: Complement]]
<div style="clear:both"></div>
[[Category: Complement inhibitor]]
__TOC__
[[Category: Module]]
</StructureSection>
[[Category: Protein structure]]
[[Category: Large Structures]]
[[Category: Vaccinia virus]]
[[Category: Vaccinia virus Copenhagen]]
[[Category: Barlow PN]]
[[Category: Bromek K]]
[[Category: Henderson CE]]
[[Category: Mullin NP]]
[[Category: Smith BO]]
[[Category: Uhrin D]]
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