ModG: Difference between revisions
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<StructureSection load='1atg' size='350' side='right' caption='Molybdate-binding protein complex with tungstate, ethylene glycol, acetate and sulfate (PDB entry [[1atg]])' scene=''> | |||
__TOC__ | __TOC__ | ||
=Introduction to ModG= | =Introduction to ModG= | ||
ModG is a cytoplasmic molybdate-binding protein exclusive to the aerobic nitrogen-fixer ''Azobacter vinelandii''.<ref name="MODGR1">PMID:11352591</ref> Molybdate is a molybdenum oxyanion (MoO42-). The group 6 element molybdenum is required by many enzymes that catalyze reactions associated with carbon, nitrogen, or sulfur metabolism.<ref name="MODGR2">PMID:21454640</ref> It is also part of the cofactor of the molybdoenzyme ModG. Not surprisingly, studies have linked ModG to molybdenum homeostasis within the cell.<ref name="MODGR1"/> | '''ModG''' is a cytoplasmic molybdate-binding protein exclusive to the aerobic nitrogen-fixer ''Azobacter vinelandii''.<ref name="MODGR1">PMID:11352591</ref> Molybdate is a molybdenum oxyanion (MoO42-). The group 6 element molybdenum is required by many enzymes that catalyze reactions associated with carbon, nitrogen, or sulfur metabolism.<ref name="MODGR2">PMID:21454640</ref> It is also part of the cofactor of the molybdoenzyme ModG. Not surprisingly, studies have linked ModG to molybdenum homeostasis within the cell.<ref name="MODGR1"/> | ||
=Structure= | =Structure= | ||
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=Fate= | =Fate= | ||
ModG is eventually degraded and incorporated into molybdopterin, a cofactor of molybdenum enzymes, or the iron-molybdenum cofactor of a nitrogenase enzyme.<ref name="MODGR1"/><ref name="MODGR2"/> Currently there is little known about cofactor biosynthesis involving the ModG protein.<ref name="MODGR1"/> | ModG is eventually degraded and incorporated into molybdopterin, a cofactor of molybdenum enzymes, or the iron-molybdenum cofactor of a nitrogenase enzyme.<ref name="MODGR1"/><ref name="MODGR2"/> Currently there is little known about cofactor biosynthesis involving the ModG protein.<ref name="MODGR1"/> | ||
</StructureSection> | |||
=3D structures of ModG= | =3D structures of ModG= | ||
