3h87: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3h87.png|left|200px]]


{{STRUCTURE_3h87|  PDB=3h87  |  SCENE=  }}
==Rv0301 Rv0300 Toxin Antitoxin Complex from Mycobacterium tuberculosis==
 
<StructureSection load='3h87' size='340' side='right'caption='[[3h87]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
===Rv0301 Rv0300 Toxin Antitoxin Complex from Mycobacterium tuberculosis===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3h87]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H87 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
[[3h87]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H87 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h87 OCA], [https://pdbe.org/3h87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h87 RCSB], [https://www.ebi.ac.uk/pdbsum/3h87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h87 ProSAT], [https://www.topsan.org/Proteins/ISFI/3h87 TOPSAN]</span></td></tr>
[[Category: Mycobacterium tuberculosis h37rv]]
</table>
[[Category: Cascio, D.]]
== Function ==
[[Category: Eisenberg, D.]]
[https://www.uniprot.org/uniprot/VAPC2_MYCTU VAPC2_MYCTU] Toxic component of a type II toxin-antitoxin (TA) system. Acts as an RNase. Upon expression in M.smegmatis inhibits translation, growth and colony formation. All its toxic effects are neutralized by coexpression with cognate antitoxin VapB2.<ref>PMID:20011113</ref>
[[Category: ISFI, Integrated Center for Structure and Function Innovation.]]
== Evolutionary Conservation ==
[[Category: Min, A.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Sawaya, M R.]]
Check<jmol>
[[Category: Integrated center for structure and function innovation]]
  <jmolCheckbox>
[[Category: Isfi]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/3h87_consurf.spt"</scriptWhenChecked>
[[Category: Protein structure initiative]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Psi-2]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Rhh motif]]
  </jmolCheckbox>
[[Category: Structural genomic]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h87 ConSurf].
[[Category: Toxin antitoxin complex]]
<div style="clear:both"></div>
[[Category: Toxin-antitoxin complex]]
== References ==
[[Category: Tuberculosis]]
<references/>
[[Category: Vapbc complex]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Cascio D]]
[[Category: Eisenberg D]]
[[Category: Min A]]
[[Category: Sawaya MR]]
Retrieved from "https://proteopedia.org/3h87"