3sad: Difference between revisions

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[[Image:3sad.jpg|left|200px]]


{{STRUCTURE_3sad| PDB=3sad | SCENE= }}
==Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 4-(2-mehtylphenyl)-2,4-dioxobutanoic acid inhibitor==
<StructureSection load='3sad' size='340' side='right'caption='[[3sad]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sad]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SAD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SAD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=040:4-(2-METHYLPHENYL)-2,4-DIOXOBUTANOIC+ACID'>040</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sad FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sad OCA], [https://pdbe.org/3sad PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sad RCSB], [https://www.ebi.ac.uk/pdbsum/3sad PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sad ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MASZ_MYCTU MASZ_MYCTU] Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA (By similarity).[HAMAP-Rule:MF_00641]


===Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 4-(2-mehtylphenyl)-2,4-dioxobutanoic acid inhibitor===
==See Also==
 
*[[Malate synthase 3D structures|Malate synthase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3sad]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SAD OCA].
[[Category: Large Structures]]
[[Category: Malate synthase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Krieger, I V.]]
[[Category: Krieger IV]]
[[Category: Sacchettini, J C.]]
[[Category: Sacchettini JC]]
[[Category: Sun, Q.]]
[[Category: Sun Q]]
[[Category: XMTB, Mycobacterium Tuberculosis Structural Proteomics Project.]]
[[Category: Inhibitor complex]]
[[Category: Malate synthase]]
[[Category: Mycobacterium tuberculosis structural proteomics project]]
[[Category: Structural genomic]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Xmtb]]
Retrieved from "https://proteopedia.org/3sad"