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[[Image:1edz.png|left|200px]]


{{STRUCTURE_1edz|  PDB=1edz  |  SCENE=  }}
==STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE==
 
<StructureSection load='1edz' size='340' side='right'caption='[[1edz]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
===STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1edz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EDZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EDZ FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1edz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1edz OCA], [https://pdbe.org/1edz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1edz RCSB], [https://www.ebi.ac.uk/pdbsum/1edz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1edz ProSAT]</span></td></tr>
[[1edz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EDZ OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/MTD1_YEAST MTD1_YEAST] Catalyzes oxidation of cytoplasmic one-carbon units for purine biosynthesis.
<ref group="xtra">PMID:010933503</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ed/1edz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1edz ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Appling, D R.]]
[[Category: Appling DR]]
[[Category: Breksa, A.]]
[[Category: Breksa A]]
[[Category: Ernst, S.]]
[[Category: Ernst S]]
[[Category: Monzingo, A F.]]
[[Category: Monzingo AF]]
[[Category: Robertus, J D.]]
[[Category: Robertus JD]]
[[Category: Dehydrogenase]]
[[Category: Folate]]
[[Category: Monofunctional]]
[[Category: Nucleotide-binding domain]]
[[Category: Oxidoreductase]]
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