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[[Image:1ee1.png|left|200px]]


{{STRUCTURE_1ee1| PDB=1ee1 | SCENE= }}
==CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD+ SYNTHETASE FROM BACILLUS SUBTILIS COMPLEXED WITH ONE MOLECULE ATP, TWO MOLECULES DEAMIDO-NAD+ AND ONE MG2+ ION==
<StructureSection load='1ee1' size='340' side='right'caption='[[1ee1]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1ee1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EE1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=DND:NICOTINIC+ACID+ADENINE+DINUCLEOTIDE'>DND</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ee1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ee1 OCA], [https://pdbe.org/1ee1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ee1 RCSB], [https://www.ebi.ac.uk/pdbsum/1ee1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ee1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NADE_BACSU NADE_BACSU] Catalyzes a key step in NAD biosynthesis, transforming deamido-NAD into NAD by a two-step reaction.[HAMAP-Rule:MF_00193]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/1ee1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ee1 ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF NH3-DEPENDENT NAD+ SYNTHETASE FROM BACILLUS SUBTILIS COMPLEXED WITH ONE MOLECULE ATP, TWO MOLECULES DEAMIDO-NAD+ AND ONE MG2+ ION===
==See Also==
 
*[[NAD synthase|NAD synthase]]
 
__TOC__
==About this Structure==
</StructureSection>
[[1ee1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EE1 OCA].
 
==Reference==
<ref group="xtra">PMID:011375500</ref><references group="xtra"/>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Brouillette, C.]]
[[Category: Large Structures]]
[[Category: Brouillette, W.]]
[[Category: Brouillette C]]
[[Category: Chattopadhyay, D.]]
[[Category: Brouillette W]]
[[Category: Delucas, L.]]
[[Category: Chattopadhyay D]]
[[Category: Devedjiev, Y.]]
[[Category: Delucas L]]
[[Category: Jedrzejas, M.]]
[[Category: Devedjiev Y]]
[[Category: Muccio, D.]]
[[Category: Jedrzejas M]]
[[Category: Singh, R.]]
[[Category: Muccio D]]
[[Category: Symersky, J.]]
[[Category: Singh R]]
[[Category: Amidotransferase]]
[[Category: Symersky J]]
[[Category: Atp pyrophosphatase]]
[[Category: Ligase]]
[[Category: Lyase]]
[[Category: Nh3 dependent]]
Retrieved from "https://proteopedia.org/1ee1"