2m0g: Difference between revisions
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==Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3 splice site Recognition== | |||
<StructureSection load='2m0g' size='340' side='right'caption='[[2m0g]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2m0g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0G FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0g OCA], [https://pdbe.org/2m0g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0g RCSB], [https://www.ebi.ac.uk/pdbsum/2m0g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0g ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SF01_HUMAN SF01_HUMAN] Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.<ref>PMID:8752089</ref> <ref>PMID:10449420</ref> <ref>PMID:9660765</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Bagdiul I]] | |||
[[Category: Kang H]] | |||
[[Category: Kern T]] | |||
[[Category: Kraemer A]] | |||
[[Category: Madl T]] | |||
[[Category: Maeusbacher N]] | |||
[[Category: Sattler M]] | |||
[[Category: Sieber SA]] | |||
[[Category: Zhang Y]] | |||
[[Category: Zou P]] | |||