4h0n: Difference between revisions
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==Crystal structure of Spodoptera frugiperda DNMT2 E260A/E261A/K263A mutant== | |||
<StructureSection load='4h0n' size='340' side='right'caption='[[4h0n]], [[Resolution|resolution]] 2.71Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4h0n]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Spodoptera_frugiperda Spodoptera frugiperda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H0N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H0N FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.712Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h0n OCA], [https://pdbe.org/4h0n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h0n RCSB], [https://www.ebi.ac.uk/pdbsum/4h0n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h0n ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TRDMT_SPOFR TRDMT_SPOFR] Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp) (By similarity). Also has DNA (cytosine-5)-methyltransferase activity (PubMed:23103599). Shows affinity for both tRNA(Asp) and DNA substrates (PubMed:23103599).[UniProtKB:O14717]<ref>PMID:23103599</ref> | |||
== | ==See Also== | ||
*[[DNA methyltransferase 3D structures|DNA methyltransferase 3D structures]] | |||
== References == | |||
== | <references/> | ||
[[ | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Spodoptera frugiperda]] | [[Category: Spodoptera frugiperda]] | ||
[[Category: Ding | [[Category: Ding J]] | ||
[[Category: Du | [[Category: Du J]] | ||
[[Category: Li | [[Category: Li S]] | ||
[[Category: Yang | [[Category: Yang H]] | ||
[[Category: Yin | [[Category: Yin J]] | ||
[[Category: Zhong | [[Category: Zhong J]] | ||