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[[Image:2ly9.jpg|left|200px]]


{{STRUCTURE_2ly9|  PDB=2ly9  |  SCENE=  }}
==Solution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907F==
 
<StructureSection load='2ly9' size='340' side='right'caption='[[2ly9]]' scene=''>
===Solution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907F===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ly9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LY9 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ly9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ly9 OCA], [https://pdbe.org/2ly9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ly9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ly9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ly9 ProSAT]</span></td></tr>
[[2ly9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LY9 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/ZHX1_HUMAN ZHX1_HUMAN] Acts as a transcriptional repressor. Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins.<ref>PMID:12237128</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Acton, T B.]]
[[Category: Large Structures]]
[[Category: Eletsky, A.]]
[[Category: Acton TB]]
[[Category: Everett, J K.]]
[[Category: Eletsky A]]
[[Category: Janjua, H.]]
[[Category: Everett JK]]
[[Category: Kohan, E.]]
[[Category: Janjua H]]
[[Category: Lee, D.]]
[[Category: Kohan E]]
[[Category: Mills, J L.]]
[[Category: Lee D]]
[[Category: Montelione, G T.]]
[[Category: Mills JL]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Montelione GT]]
[[Category: Pulavarti, S V.S R.K.]]
[[Category: Pulavarti SVSRK]]
[[Category: Szyperski, T.]]
[[Category: Szyperski T]]
[[Category: Xiao, R.]]
[[Category: Xiao R]]
[[Category: Xu, X.]]
[[Category: Xu X]]
[[Category: Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]
[[Category: Transcription]]

Latest revision as of 05:55, 15 May 2024

Solution NMR Structure of Homeobox 2 Domain from Human ZHX1 repressor, Northeast Structural Genomics Consortium (NESG) Target HR7907F

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