1ey3: Difference between revisions

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[[Image:1ey3.png|left|200px]]


{{STRUCTURE_1ey3| PDB=1ey3 | SCENE= }}
==STRUCTURE OF ENOYL-COA HYDRATASE COMPLEXED WITH THE SUBSTRATE DAC-COA==
<StructureSection load='1ey3' size='340' side='right'caption='[[1ey3]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1ey3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EY3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EY3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DAK:4-(N,N-DIMETHYLAMINO)CINNAMOYL-COA'>DAK</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ey3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ey3 OCA], [https://pdbe.org/1ey3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ey3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ey3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ey3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ECHM_RAT ECHM_RAT] Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ey/1ey3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ey3 ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF ENOYL-COA HYDRATASE COMPLEXED WITH THE SUBSTRATE DAC-COA===
==See Also==
 
*[[Enoyl-CoA hydratase 3D structures|Enoyl-CoA hydratase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[1ey3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EY3 OCA].
[[Category: Large Structures]]
 
==Reference==
<ref group="xtra">PMID:011851409</ref><references group="xtra"/>
[[Category: Enoyl-CoA hydratase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Anderson, V E.]]
[[Category: Anderson VE]]
[[Category: Bahnson, B J.]]
[[Category: Bahnson BJ]]
[[Category: Petsko, G A.]]
[[Category: Petsko GA]]
[[Category: Beta-elimination]]
[[Category: Beta-oxidation]]
[[Category: Concerted reaction]]
[[Category: Crotonase]]
[[Category: Enoyl-coa hydratase]]
[[Category: Fatty acid metabolism]]
[[Category: Lyase]]
[[Category: Syn-addition]]

Latest revision as of 13:22, 13 March 2024

STRUCTURE OF ENOYL-COA HYDRATASE COMPLEXED WITH THE SUBSTRATE DAC-COA

1ey3, resolution 2.30Å

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