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[[Image:1f6y.png|left|200px]]


{{STRUCTURE_1f6y|  PDB=1f6y  |  SCENE=  }}
==MAD CRYSTAL STRUCTURE ANALYSIS OF METHYLTETRAHYDROFOLATE: CORRINOID/IRON-SULFUR PROTEIN METHYLTRANSFERASE (METR)==
 
<StructureSection load='1f6y' size='340' side='right'caption='[[1f6y]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===MAD CRYSTAL STRUCTURE ANALYSIS OF METHYLTETRAHYDROFOLATE: CORRINOID/IRON-SULFUR PROTEIN METHYLTRANSFERASE (METR)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1f6y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Moorella_thermoacetica_ATCC_39073 Moorella thermoacetica ATCC 39073]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F6Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F6Y FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f6y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f6y OCA], [https://pdbe.org/1f6y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f6y RCSB], [https://www.ebi.ac.uk/pdbsum/1f6y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f6y ProSAT]</span></td></tr>
[[1f6y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Moorella_thermoacetica Moorella thermoacetica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F6Y OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/ACSE_MOOTH ACSE_MOOTH] Methyltransferase that mediates the transfer of a N5-methyl group of (6S)-methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein in the anaerobic acetyl-CoA pathway (Wood-Ljungdahl pathway) of carbon monoxide and carbon dioxide fixation.<ref>PMID:17172470</ref> <ref>PMID:22419154</ref> <ref>PMID:7928975</ref>
<ref group="xtra">PMID:010997901</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Moorella thermoacetica]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Doukov, T I.]]
Check<jmol>
[[Category: Ragsdale, S W.]]
  <jmolCheckbox>
[[Category: Seravalli, J.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f6/1f6y_consurf.spt"</scriptWhenChecked>
[[Category: Stezowski, J J.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Carbon dioxide fixation]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Cobalamin]]
  </jmolCheckbox>
[[Category: Homodimer]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f6y ConSurf].
[[Category: Methyltatrahydrofolate]]
<div style="clear:both"></div>
[[Category: Methyltransferase]]
== References ==
[[Category: One-carbon metabolism]]
<references/>
[[Category: Tim barrel]]
__TOC__
[[Category: Transferase]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Moorella thermoacetica ATCC 39073]]
[[Category: Doukov TI]]
[[Category: Ragsdale SW]]
[[Category: Seravalli J]]
[[Category: Stezowski JJ]]
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