TonB: Difference between revisions

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{{STRUCTURE_1ihr|  PDB=1ihr | SIZE=400| SCENE= |right|CAPTION=E. coli TonB C-terminal dimer complex with Br- ions (dark red), [[1ihr]] }}
<StructureSection load='1ihr' size='350' side='right' scene='' caption='E. coli TonB C-terminal dimer complex with Br- ions (dark red) (PDB code [[1ihr]])'>


==Structure==
==Structure==
The structure to the right [[1ihr]] shows the structure of TonB C-terminal.  The protein spans the periplasm <ref>PMID: 16741125</ref>, with the C-terminus of TonB spanning from residues ~150 to 239<ref name='Postle'>PMID: 21179522</ref>.  For more details on the Ton system see [[Ton]].
'''TonB''' spans the periplasm <ref>PMID: 16741125</ref>, with the C-terminus of TonB spanning from residues ~150 to 239<ref name='Postle'>PMID: 21179522</ref>.  For more details on the Ton system see [[Ton]].


==Function==
==Function==
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===BtuB-TonB Complex===
===BtuB-TonB Complex===


 
<StructureSection load='2gsk' size='350' side='right' scene='BtuB-TonB_Complex/Btubtonbcomplex/1' caption='E. coli TonB C-terminal (green) complex with vitamin B12 transporter BtuB (grey) (PDB code [[2gsk]])'>
{{STRUCTURE_2gsk|  PDB=2gsk | SIZE=400| SCENE=BtuB-TonB_Complex/Btubtonbcomplex/1 |right|CAPTION=E. coli TonB C-terminal (green) complex with vitamin B12 transporter BtuB (grey), [[2gsk]] }}
As shown in the 3D structure to the right (2GSK), TonB complexes with [[BtuB]] in order to aid the transport of nutrients such as cobalamins<ref name='Cadieux'>PMID 11029413</ref> across the outer membrane by incorporating the proton-motive force into the outer membrane.<ref name='Shultis'>PMID: 16741124</ref>  TonB attaches to BtuB on the periplasmic side of the 614 amino acid BtuB protein<ref name='Shultis'> PMID: 16741124</ref>.
As shown in the 3D structure to the right (2GSK), TonB complexes with [[BtuB]] in order to aid the transport of nutrients such as cobalamins<ref name='Cadieux'>PMID 11029413</ref> across the outer membrane by incorporating the proton-motive force into the outer membrane.<ref name='Shultis'>PMID: 16741124</ref>  TonB attaches to BtuB on the periplasmic side of the 614 amino acid BtuB protein<ref name='Shultis'> PMID: 16741124</ref>.
 
</StructureSection>
==3D structures of TonB==
==3D structures of TonB==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}


[[1ihr]], [[1qxx]], [[1u07]] – EcTonB C terminal – ''Escherichia coli''<br />
[[1ihr]], [[1qxx]], [[1u07]] – EcTonB C terminal – ''Escherichia coli''<br />
[[1xx3]] - EcTonB C terminal – NMR<br />
[[1xx3]], [[5lw8]] - EcTonB C terminal – NMR<br />
[[2grx]] - EcTonB + ferrichrome-iron receptor<br />
[[2grx]] - EcTonB + ferrichrome-iron receptor<br />
[[2ivz]] - EcTonB + colicin-E9 peptide<br />
[[2gsk]] - EcTonB C terminal + vitamin B12 transporter BtuB<br />
[[2gsk]] - EcTonB C terminal + vitamin B12 transporter BtuB<br />
[[2k9k]] – EcTonB2 C terminal – ''Listonella anguillarum''
[[2k9k]] – TonB2 C terminal – ''Listonella anguillarum''<br />
 
[[6fip]] - PaTonB C terminal – ''Pseudomonas aeruginosa'' - NMR<br />
[[6i97]] - PaTonB C terminal + TonB-dependent receptor <br />
[[5lw8]], [[6sly]] - TonB C terminal – ''Helicobacter pylori'' - NMR<br />


== References==
== References==
<references/>
<references/>
[[Category:Topic Page]]
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