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[[Image:1g0o.png|left|200px]]


{{STRUCTURE_1g0o|  PDB=1g0o  |  SCENE=  }}
==STRUCTURE OF TRIHYDROXYNAPHTHALENE REDUCTASE IN COMPLEX WITH NADPH AND PYROQUILON==
 
<StructureSection load='1g0o' size='340' side='right'caption='[[1g0o]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
===STRUCTURE OF TRIHYDROXYNAPHTHALENE REDUCTASE IN COMPLEX WITH NADPH AND PYROQUILON===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1g0o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyricularia_grisea Pyricularia grisea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G0O FirstGlance]. <br>
{{ABSTRACT_PUBMED_11342131}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PYQ:PYROQUILON'>PYQ</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g0o OCA], [https://pdbe.org/1g0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g0o RCSB], [https://www.ebi.ac.uk/pdbsum/1g0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g0o ProSAT]</span></td></tr>
[[1g0o]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Magnaporthe_grisea Magnaporthe grisea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G0O OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/T4HR_MAGO7 T4HR_MAGO7] Catalyzes the NADPH-dependent reduction of 1,3,6,8-tetrahydroxynaphthalene (T4HN) into (+)-scytalone and 1,3,8-trihydroxynaphthalene into (-)-vermelone. This enzyme is the biochemical target of several commercially important fungicides which are used to prevent blast disease in rice plants.
<ref group="xtra">PMID:011342131</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Magnaporthe grisea]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Tetrahydroxynaphthalene reductase]]
Check<jmol>
[[Category: Basarab, G S.]]
  <jmolCheckbox>
[[Category: Gatenby, A A.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/1g0o_consurf.spt"</scriptWhenChecked>
[[Category: Jordan, D B.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Liao, D.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Valent, B.]]
  </jmolCheckbox>
[[Category: Dinucleotide binding fold]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g0o ConSurf].
[[Category: Oxidoreductase]]
<div style="clear:both"></div>
[[Category: Protein-nadph-active site inhibitor complex]]
__TOC__
[[Category: Short chain dehydrogenase]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyricularia grisea]]
[[Category: Basarab GS]]
[[Category: Gatenby AA]]
[[Category: Jordan DB]]
[[Category: Liao D]]
[[Category: Valent B]]
Retrieved from "https://proteopedia.org/1g0o"