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[[Image:1gql.png|left|200px]]


{{STRUCTURE_1gql| PDB=1gql | SCENE= }}
==Structure of Pseudomonas cellulosa alpha-D-glucuronidase complexed with glucuronic acid and xylotriose==
<StructureSection load='1gql' size='340' side='right'caption='[[1gql]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1gql]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GQL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gql OCA], [https://pdbe.org/1gql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gql RCSB], [https://www.ebi.ac.uk/pdbsum/1gql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gql ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AGUA_CELJU AGUA_CELJU] Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. It catalyzes the cleavage of the alpha-1,2-glycosidic bond at the non-reducing end of 4-O-methyl-D-glucuronic acid (4-O-MeGlcA) side chain of short xylooligosaccharides and releases 4-O-methylglucuronic acid. It can also hydrolyze small soluble oligosaccharides such as dobiouronic acid, aldotriouronic acid, aldotetraouronic acid, and aldopentaouronic acid.<ref>PMID:11937059</ref> <ref>PMID:12169619</ref> <ref>PMID:12654910</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/1gql_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gql ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF PSEUDOMONAS CELLULOSA ALPHA-D-GLUCURONIDASE COMPLEXED WITH GLUCURONIC ACID AND XYLOTRIOSE===
==See Also==
 
*[[Glucuronisidase 3D structures|Glucuronisidase 3D structures]]
{{ABSTRACT_PUBMED_11937059}}
== References ==
 
<references/>
==About this Structure==
__TOC__
[[1gql]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cellvibrio_japonicus Cellvibrio japonicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQL OCA].
</StructureSection>
 
==Reference==
<ref group="xtra">PMID:011937059</ref><references group="xtra"/>
[[Category: Alpha-glucuronidase]]
[[Category: Cellvibrio japonicus]]
[[Category: Cellvibrio japonicus]]
[[Category: Davies, G J.]]
[[Category: Large Structures]]
[[Category: Gilbert, H J.]]
[[Category: Davies GJ]]
[[Category: Nagy, T.]]
[[Category: Gilbert HJ]]
[[Category: Nurizzo, D.]]
[[Category: Nagy T]]
[[Category: Glucuronic acid]]
[[Category: Nurizzo D]]
[[Category: Glucuronidase]]
[[Category: Glycoside hydrolase]]
[[Category: Hydrolase]]
[[Category: Xylotriose]]
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