1htj: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
m Protected "1htj" [edit=sysop:move=sysop]
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(7 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1htj.png|left|200px]]


{{STRUCTURE_1htj|  PDB=1htj  |  SCENE=  }}
==STRUCTURE OF THE RGS-LIKE DOMAIN FROM PDZ-RHOGEF==
 
<StructureSection load='1htj' size='340' side='right'caption='[[1htj]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===STRUCTURE OF THE RGS-LIKE DOMAIN FROM PDZ-RHOGEF===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1htj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HTJ FirstGlance]. <br>
{{ABSTRACT_PUBMED_11470431}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1htj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1htj OCA], [https://pdbe.org/1htj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1htj RCSB], [https://www.ebi.ac.uk/pdbsum/1htj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1htj ProSAT]</span></td></tr>
[[1htj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTJ OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/ARHGB_HUMAN ARHGB_HUMAN] May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
<ref group="xtra">PMID:011470431</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ht/1htj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1htj ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chikumi, H.]]
[[Category: Large Structures]]
[[Category: Derewenda, Z S.]]
[[Category: Chikumi H]]
[[Category: Gutkind, J S.]]
[[Category: Derewenda ZS]]
[[Category: Lewis, M E.]]
[[Category: Gutkind JS]]
[[Category: Longenecker, K L.]]
[[Category: Lewis ME]]
[[Category: Gef]]
[[Category: Longenecker KL]]
[[Category: Guanine nucleotide exchange factor]]
[[Category: Regulator of g protein signaling]]
[[Category: Rgs-like]]
[[Category: Signaling protein]]
Retrieved from "https://proteopedia.org/1htj"