1g2a: Difference between revisions
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==THE CRYSTAL STRUCTURE OF E.COLI PEPTIDE DEFORMYLASE COMPLEXED WITH ACTINONIN== | |||
<StructureSection load='1g2a' size='340' side='right'caption='[[1g2a]], [[Resolution|resolution]] 1.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1g2a]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G2A FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g2a OCA], [https://pdbe.org/1g2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g2a RCSB], [https://www.ebi.ac.uk/pdbsum/1g2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g2a ProSAT]</span></td></tr> | ||
[[1g2a]] is a 3 chain structure with sequence from [ | </table> | ||
== Function == | |||
== | [https://www.uniprot.org/uniprot/DEF_ECOLI DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163] | ||
< | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g2/1g2a_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g2a ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Baker | [[Category: Baker PJ]] | ||
[[Category: Barynin | [[Category: Barynin V]] | ||
[[Category: Beckett | [[Category: Beckett P]] | ||
[[Category: Brown | [[Category: Brown A]] | ||
[[Category: Catlin | [[Category: Catlin C]] | ||
[[Category: Clements | [[Category: Clements JM]] | ||
[[Category: Hunter | [[Category: Hunter MG]] | ||
[[Category: Lobell | [[Category: Lobell M]] | ||
[[Category: Palan | [[Category: Palan S]] | ||
[[Category: Rice | [[Category: Rice DW]] | ||
[[Category: Rodgers | [[Category: Rodgers HF]] | ||
[[Category: Thomas | [[Category: Thomas W]] | ||
[[Category: Whittaker | [[Category: Whittaker M]] | ||
Latest revision as of 07:21, 7 February 2024
THE CRYSTAL STRUCTURE OF E.COLI PEPTIDE DEFORMYLASE COMPLEXED WITH ACTINONIN
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