4i13: Difference between revisions

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New page: '''Unreleased structure''' The entry 4i13 is ON HOLD Authors: Oyen, D., Steyaert, J., Barlow, J.N. Description: Nanobody ca1697 binding to the DHFR.folate binary complex
 
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'''Unreleased structure'''


The entry 4i13 is ON HOLD
==Nanobody ca1697 binding to the DHFR.folate binary complex==
<StructureSection load='4i13' size='340' side='right'caption='[[4i13]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4i13]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I13 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I13 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i13 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i13 OCA], [https://pdbe.org/4i13 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i13 RCSB], [https://www.ebi.ac.uk/pdbsum/4i13 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i13 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.


Authors: Oyen, D., Steyaert, J., Barlow, J.N.
==See Also==
 
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
Description: Nanobody ca1697 binding to the DHFR.folate binary complex
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Lama glama]]
[[Category: Large Structures]]
[[Category: Barlow JN]]
[[Category: Oyen D]]
[[Category: Steyaert J]]
Retrieved from "https://proteopedia.org/4i13"