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[[Image:2yan.png|left|200px]]


{{STRUCTURE_2yan|  PDB=2yan  |  SCENE=  }}
==Crystal structure of the second glutaredoxin domain of human TXNL2==
 
<StructureSection load='2yan' size='340' side='right'caption='[[2yan]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===Crystal structure of the second glutaredoxin domain of human TXNL2===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2yan]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YAN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YAN FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[2yan]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YAN OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yan FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yan OCA], [https://pdbe.org/2yan PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yan RCSB], [https://www.ebi.ac.uk/pdbsum/2yan PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yan ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLRX3_HUMAN GLRX3_HUMAN] Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Allerston, C.]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Allerston C]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Cocking, R.]]
[[Category: Bountra C]]
[[Category: Delft, F Von.]]
[[Category: Cocking R]]
[[Category: Edwards, A.]]
[[Category: Edwards A]]
[[Category: Johansson, C.]]
[[Category: Johansson C]]
[[Category: Krojer, T.]]
[[Category: Krojer T]]
[[Category: Muniz, J R.C.]]
[[Category: Muniz JRC]]
[[Category: Oppermann, U.]]
[[Category: Oppermann U]]
[[Category: Vollmar, M.]]
[[Category: Vollmar M]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Oxidoreductase]]
[[Category: Von Delft F]]
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