4b8w: Difference between revisions

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[[Image:4b8w.png|left|200px]]


{{STRUCTURE_4b8w|  PDB=4b8w  |  SCENE=  }}
==Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form==
 
<StructureSection load='4b8w' size='340' side='right'caption='[[4b8w]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
===Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4b8w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B8W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B8W FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
[[4b8w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B8W OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b8w OCA], [https://pdbe.org/4b8w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b8w RCSB], [https://www.ebi.ac.uk/pdbsum/4b8w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b8w ProSAT]</span></td></tr>
[[Category: GDP-L-fucose synthase]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/FCL_HUMAN FCL_HUMAN] Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Bunkoczi, G.]]
[[Category: Bountra C]]
[[Category: Carpenter, E.]]
[[Category: Bunkoczi G]]
[[Category: Chaikuat, A.]]
[[Category: Carpenter E]]
[[Category: Delft, F Von.]]
[[Category: Chaikuat A]]
[[Category: Edwards, A.]]
[[Category: Edwards A]]
[[Category: Kavanagh, K.]]
[[Category: Kavanagh K]]
[[Category: Krojer, T.]]
[[Category: Krojer T]]
[[Category: Oppermann, U.]]
[[Category: Oppermann U]]
[[Category: Pike, A.]]
[[Category: Pike A]]
[[Category: Rojkova, A.]]
[[Category: Rojkova A]]
[[Category: Shafqat, N.]]
[[Category: Shafqat N]]
[[Category: Vollmar, M.]]
[[Category: Vollmar M]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Yue, W W.]]
[[Category: Yue WW]]
[[Category: Oxidoreductase]]
[[Category: Von Delft F]]
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