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[[Image:2ksd.png|left|200px]]


{{STRUCTURE_2ksd|  PDB=2ksd  |  SCENE=  }}
==Backbone structure of the membrane domain of E. coli histidine kinase receptor ArcB, Center for Structures of Membrane Proteins (CSMP) target 4310C==
 
<StructureSection load='2ksd' size='340' side='right'caption='[[2ksd]]' scene=''>
===Backbone structure of the membrane domain of E. coli histidine kinase receptor ArcB, Center for Structures of Membrane Proteins (CSMP) target 4310C===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ksd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KSD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KSD FirstGlance]. <br>
{{ABSTRACT_PUBMED_20498088}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ksd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ksd OCA], [https://pdbe.org/2ksd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ksd RCSB], [https://www.ebi.ac.uk/pdbsum/2ksd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ksd ProSAT]</span></td></tr>
==About this Structure==
</table>
[[2ksd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KSD OCA].  
== Function ==
[[Category: Escherichia coli k-12]]
[https://www.uniprot.org/uniprot/ARCB_ECOLI ARCB_ECOLI] Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His-717 and Asp-576.
[[Category: Histidine kinase]]
== Evolutionary Conservation ==
[[Category: CSMP, Center for Structures of Membrane Proteins.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Choe, S.]]
Check<jmol>
[[Category: Hwang, E.]]
  <jmolCheckbox>
[[Category: Jeon, Y.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ks/2ksd_consurf.spt"</scriptWhenChecked>
[[Category: Kefala, G.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Klammt, C.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Kwiatkowski, W.]]
  </jmolCheckbox>
[[Category: Maslennikov, I.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ksd ConSurf].
[[Category: Cell inner membrane]]
<div style="clear:both"></div>
[[Category: Cell membrane]]
__TOC__
[[Category: Cell-free synthesis]]
</StructureSection>
[[Category: Center for structures of membrane protein]]
[[Category: Escherichia coli K-12]]
[[Category: Csmp]]
[[Category: Large Structures]]
[[Category: Histidine kinase receptor]]
[[Category: Choe S]]
[[Category: Kinase]]
[[Category: Hwang E]]
[[Category: Membrane domain]]
[[Category: Jeon Y]]
[[Category: Methods development]]
[[Category: Kefala G]]
[[Category: Protein structure initiative]]
[[Category: Klammt C]]
[[Category: Psi-2]]
[[Category: Kwiatkowski W]]
[[Category: Structural genomic]]
[[Category: Maslennikov I]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transferase]]
[[Category: Transmembrane]]
[[Category: Two-component regulatory system]]
[[Category: Two-helical hairpin]]

Latest revision as of 06:48, 1 May 2024

Backbone structure of the membrane domain of E. coli histidine kinase receptor ArcB, Center for Structures of Membrane Proteins (CSMP) target 4310C

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