1gwm: Difference between revisions

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New page: left|200px<br /> <applet load="1gwm" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gwm, resolution 1.15Å" /> '''CARBOHYDRATE BINDIN...
 
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[[Image:1gwm.gif|left|200px]]<br />
<applet load="1gwm" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1gwm, resolution 1.15&Aring;" />
'''CARBOHYDRATE BINDING MODULE FAMILY29 COMPLEXED WITH GLUCOHEXAOSE'''<br />


==Overview==
==Carbohydrate binding module family29 complexed with glucohexaose==
Carbohydrate-protein recognition is central to many biological processes., Enzymes that act on polysaccharide substrates frequently contain, noncatalytic domains, "carbohydrate-binding modules" (CBMs), that target, the enzyme to the appropriate substrate. CBMs that recognize specific, plant structural polysaccharides are often able to accommodate both the, variable backbone and the side-chain decorations of heterogeneous ligands., "CBM29" modules, derived from a noncatalytic component of the Piromyces, equi cellulase/hemicellulase complex, provide an example of this selective, yet flexible recognition. They discriminate strongly against some, polysaccharides while remaining relatively promiscuous toward both, beta-1,4-linked manno- and cello-oligosaccharides. This feature may, reflect ... [[http://ispc.weizmann.ac.il/pmbin/getpm?12391332 (full description)]]
<StructureSection load='1gwm' size='340' side='right'caption='[[1gwm]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1gwm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Piromyces_sp._'equi' Piromyces sp. 'equi']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GWM FirstGlance]. <br>
1GWM is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Piromyces_equi Piromyces equi]] with CO and EDO as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GWM OCA]].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gwm OCA], [https://pdbe.org/1gwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gwm RCSB], [https://www.ebi.ac.uk/pdbsum/1gwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gwm ProSAT]</span></td></tr>
Promiscuity in ligand-binding: The three-dimensional structure of a Piromyces carbohydrate-binding module, CBM29-2, in complex with cello- and mannohexaose., Charnock SJ, Bolam DN, Nurizzo D, Szabo L, McKie VA, Gilbert HJ, Davies GJ, Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14077-82. Epub 2002 Oct 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12391332 12391332]
</table>
[[Category: Piromyces equi]]
== Function ==
[[Category: Single protein]]
[https://www.uniprot.org/uniprot/Q9C171_PIREQ Q9C171_PIREQ]  
[[Category: Charnock, S.J.]]
__TOC__
[[Category: Davies, G.J.]]
</StructureSection>
[[Category: Nurizzo, D.]]
[[Category: Large Structures]]
[[Category: CO]]
[[Category: Piromyces sp. 'equi']]
[[Category: EDO]]
[[Category: Charnock SJ]]
[[Category: carbohydrate binding domain]]
[[Category: Davies GJ]]
[[Category: cellohexaose]]
[[Category: Nurizzo D]]
[[Category: cellulosome]]
[[Category: glucomannan]]
[[Category: mannohexaose]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 16:17:16 2007''

Latest revision as of 06:28, 1 May 2024

Carbohydrate binding module family29 complexed with glucohexaose

1gwm, resolution 1.15Å

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